This year millions of people will take psychedelics. For many, this will produce entirely positive and potentially life changing experiences. For some, however, the experience will be challenging. The power of psychedelics to alter one’s mental state creates a situation where a vast range of outcomes are possible, depending on one’s set and setting – from transformative healing to intoxicated accidents. For anyone who turns to psychedelics, one concept in particular should be at the forefront of their minds: harm reduction.